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Home > Methotrexate > (S)-1-ethyl-5-methyl (4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamate
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(S)-1-ethyl-5-methyl (4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamate

(S)-1-ethyl-5-methyl (4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamate

API CATEGORY Methotrexate Impurity
APPEARANCE yellow solid
CAT Number DCTI-C-003972
CAS NUMBER NA
IUPAC NAME 1-ethyl 5-methyl (4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamate
MOLECULAR FORMULA C23H28N8O5
MOLECULAR WEIGHT 496.53
SOLUBILITY Acetonitrile:water(1:1)
STORAGE CONDITION 2-8°C
SYNONYMS Methotrexate 1-ethyl-5-Methyl Ester Impurity

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Methotrexate Impurity H

  • Molecular Formula C21H24N8O5
  • Molecular Weight 468.47

(4-(Methylamino)benzoyl)-D-glutamic acid

  • MOLECULAR FORMULA C13H16N2O5
  • MOLECULAR WEIGHT 280.28

N-(4-nitrophenyl)-2-chloro-N-methylacetamide

  • MOLECULAR FORMULA C9H9ClN2O3
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Methotrexate Impurity B

  • Molecular Formula C19H20N8O5
  • Molecular Weight 440.41

Methotrexate Impurity I

  • Molecular Formula C21H24N8O5 (Free base) 22H26N8O7(Salt)
  • Molecular Weight 468.47 (Free base) 514.50 (Salt)

Methotrexate Dimethylester Hydrochloride

  • MOLECULAR FORMULA C22H27ClN8O5 (HCl Salt);C22H26N8O5 (Free base)
  • MOLECULAR WEIGHT 482.50 (Free base);518.96 (HCl Salt)

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