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Ziprasidone Related Compound B

  • CAT Number DCTI-C-1390
  • CAS Number 1159977-56-6
  • Molecular Formula C21H19ClN4O2S
  • Molecular Weight 426.92

Ziprasidone Related Compound C

  • CAT Number DCTI-C-1262
  • CAS Number 1303996-68-0
  • Molecular Formula C42H40Cl2N8O3S2
  • Molecular Weight 839.86

General Information

Ziprasidone Impurities and Ziprasidone

Daicel Pharma is a trusted provider of quality Ziprasidone impurity standards, including Ziprasidone Related Compound B and Ziprasidone Related Compound C.  These impurities are crucial in meticulously evaluating the quality, stability, and safety of the active pharmaceutical ingredient, Ziprasidone. Furthermore, Daicel Pharma customizes Ziprasidone impurities to meet client specifications. With global shipping capabilities, these impurities can be conveniently delivered to customers worldwide, providing unparalleled convenience.

Ziprasidone [CAS: 146939-27-7] is an atypical antipsychotic for treating schizophrenia and bipolar disorder.

Ziprasidone: Use and Commercial Availability 

Ziprasidone treats schizophrenia and acts as monotherapy for managing acute manic or mixed episodes associated with bipolar I disorder. It combines with lithium or valproate for the maintenance treatment of bipolar I disorder.

Ziprasidone is available under the brand Geodon, which contains the active ingredient Ziprasidone.

Ziprasidone Structure and Mechanism of ActionZiprasidone Structure and Mechanism of Action

The chemical name of Ziprasidone is 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one. Its chemical formula is C21H21ClN4OS, and its molecular weight is approximately 412.9 g/mol.

Ziprasidone binds to dopamine-2 and serotonin-2A receptors contributing to its antidepressant activity.

Ziprasidone Impurities and Synthesis

Ziprasidone impurities can arise during synthesis1 due to the storage or use of specific raw materials and intermediates in manufacturing. These impurities encompass related compounds, degradation products, and process impurities. Stringent quality control measures and analytical methods are crucial to ensure the purity and safety of Ziprasidone for patient use.

Daicel Pharma provides a comprehensive Certificate of Analysis (CoA) for Ziprasidone impurity standards, such as   Ziprasidone Related Compound B and Ziprasidone Related Compound C. The CoA includes detailed characterization data such as 1H NMR, 13C NMR, IR, MASS, and HPLC purity2. Additionally, upon delivery, we give 13C-DEPT. Daicel possesses the technology and expertise to synthesize any unknown Ziprasidone impurity or degradation product.


Frequently Asked Questions

Impurities in Ziprasidone can affect the drug's bioavailability and its therapeutic effect.

Impurities in Ziprasidone can come from the starting materials, intermediates, degradation products, or residual solvents.

The recommendation is to store Ziprasidone impurities at room temperature, within 2-8 °C.

DMSO is the solvent used in analyzing impurities in Ziprasidone.

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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