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  • CAS NUMBER 133690-91-2


  • CAT Number DCTI-C-1639
  • CAS Number 2763750-28-1
  • Molecular Formula C14H12N4O
  • Molecular Weight 252.28

4′-(azidomethyl)-[1,1′-biphenyl]-2-carboxylic acid

  • CAT Number DCTI-C-1640
  • CAS Number 2758005-15-9
  • Molecular Formula C14H11N3O2
  • Molecular Weight 253.26


  • CAT Number DCTI-C-1637
  • CAS Number 114772-54-2
  • Molecular Formula C14H10BrN
  • Molecular Weight 272.14


  • CAT Number DCTI-C-1216
  • CAS Number 152708-24-2
  • Molecular Formula C14H11N7
  • Molecular Weight 277.29


  • CAT Number DCTI-C-1302
  • CAS Number 124750-51-2
  • Molecular Formula C33H25BrN4
  • Molecular Weight 557.5


  • CAT Number DCTI-C-1304
  • CAS Number 358685-13-9
  • Molecular Formula C33H24Br2N4
  • Molecular Weight 636.39

Desvaleryl Valsartan N-Nitroso Impurity

  • CAS NUMBER 2254485-68-0


  • CAT Number DCTI-C-037
  • CAS Number 137862-87-4
  • Molecular Formula C24H29N5O3
  • Molecular Weight 435.53
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General Information

Valsartan Impurities and Valsartan

Daicel Pharma is a trusted provider of quality Valsartan impurity standards, including 4′-(azidomethyl)-[1,1′-biphenyl]-2-carboxamide,4′-(bromomethyl)-[1,1′-biphenyl]-2-carbonitrile, R-Valsartan, Valsartan Impurity F, Valsartan Related compound B, and many more. These impurities are crucial in meticulously evaluating the quality, stability, and safety of the active pharmaceutical ingredient, Valsartan. Furthermore, Daicel Pharma customizes Valsartan impurities, guaranteeing that it meets client specifications. With global shipping capabilities, these impurities can be conveniently delivered to customers worldwide, offering unparalleled convenience.

Valsartan [CAS: 137862-53-4] treats hypertension and lowers the chances of cardiovascular incidents such as strokes and heart attacks. It treats heart failure in patients intolerant of angiotensin-converting enzyme (ACE) inhibitors.

Valsartan: Use and Commercial Availability 

Valsartan is an angiotensin II receptor blocker used alone or combined with other antihypertensive agents to treat hypertension and reduce cardiovascular mortality after myocardial infarction. It lowers blood pressure and reduces the risk of cardiovascular events such as strokes and heart attacks. Valsartan is available under the brand names Diovan and Prexxartan.

Valsartan Structure and Mechanism of ActionValsartan Structure and Mechanism of Action

The chemical name of Valsartan is N-(1-Oxopentyl)-N-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-L-valine. Its chemical formula is C24H29N5O3, and its molecular weight is approximately 435.5 g/mol.

Valsartan selectively blocks the binding of angiotensin II to the AT1 receptor in many tissues. It prevents the vasoconstrictor and aldosterone-secreting effects of angiotensin II.

Valsartan Impurities and Synthesis 

Valsartan impurities can arise during synthesis1 due to the storage or use of specific raw materials and intermediates in manufacturing. These impurities encompass related compounds, degradation products, and process impurities. Stringent quality control measures and analytical methods are crucial to ensure the purity and safety of Valsartan for patient use.

Daicel Pharma provides a comprehensive Certificate of Analysis (CoA) for Valsartan impurity standards, such as 4′-(azidomethyl)-[1,1′-biphenyl]-2-carboxamide,4′-(bromomethyl)-[1,1′-biphenyl]-2-carbonitrile, R-Valsartan, Valsartan Impurity F, Valsartan Related compound B, and many more. The CoA includes detailed characterization data such as 1H NMR, 13C NMR, IR, MASS, and HPLC purity2. Additionally, upon delivery, we give 13C-DEPT. Daicel possesses the technology and expertise to synthesize any unknown Valsartan impurity or degradation product. We also offer labeled compounds to quantify the efficacy of generic Valsartan. For bioanalytical research and BA/BE studies, Daicel supplies highly pure S-Valsartan-D9, deuterium-labeled compounds of Valsartan.


Frequently Asked Questions

High-performance liquid chromatography (HPLC) and LCMS/ MS are employed to separate and analyze the impurities of Valsartan.

Impurities found in Valsartan can be classified into several categories, which include process-related contaminants, degradation products, residual solvents, and genotoxic impurities.

Valsartan impurities can change over time, influenced by storage conditions, exposure to light, and elevated temperatures.

The recommendation is to store Valsartan impurities at room temperature, within 2-8 °C.

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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