Sulpiride

General Information

Sulpiride Impurities and Sulpiride 

Daicel Pharma offers the best quality Sulpiride impurities, such as Sulpiride Impurity 9. It is vital for evaluating Sulpiride quality, stability, and biological safety. Furthermore, Daicel Pharma specializes in the custom synthesis of Sulpiride impurities and ensures their worldwide delivery.

Sulpiride [CAS: 15676-16-1] a substituted benzamide derivative, acts as an antipsychotic agent. It treats schizophrenia and reduces symptoms associated with Gilles de la Tourette syndrome.

Sulpiride: Use and Commercial Availability  

Sulpiride primarily treats schizophrenia. In addition, it treats patients with tics associated with Gilles de la Tourette syndrome. It is an antiemetic and an antidepressant. Sulpiride is a part of the treatment for patients suffering from mental illnesses. Many generic manufacturers sell Sulpiride under various names. Sulpiride is available under brand names like Sulpyrid, Neogama, Omperan, Dobren, Meresa, etc.

Sulpiride Structure and Mechanism of Action

The chemical name of Sulpiride is 5-(Aminosulfonyl)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide. The chemical formula for Sulpiride is C15H23N3O4S, and its molecular weight is approximately 341.43 g/mol.

Sulpiride is a selective dopamine D2 receptor antagonist. It interacts with specific amino acid residues of the dopamine receptors in the brain.

Sulpiride Impurities and Synthesis

Impurities may form during the synthesis of Sulpiride 1, which affects drug safety and efficacy. These impurities form during the synthesis, storage, or degradation of Sulpiride. So, Sulpiride impurities must be controlled and monitored throughout the drug’s lifecycle.

Daicel Pharma offers a comprehensive Certificate of Analysis (CoA) for Sulpiride impurities, which includes Sulpiride Impurity 9. The issued CoA is from a cGMP-compliant analytical facility. It contains characterization data such as 1H NMR, 13C NMR, IR, MASS, and HPLC purity2. We give additional spectral data on request. Daicel Pharma can prepare any unidentified Sulpiride impurity or degradation product. In addition, Daicel Pharma offers highly purified isotope-labeled standards of Sulpiride for bioanalytical research and BA/BE studies. We also provide a complete characterization report on delivery.