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Progesterone
References
FAQ's
References
- Sundararaman, Padmanabhan; Djerassi, Carl, A convenient synthesis of progesterone from stigmasterol, Journal of Organic Chemistry, Volume: 42, Issue: 22, Pages: 3633-4, 1977
- Wyman, Heather; Sommerville, Ian F., Description and evaluation of a simple technique for determination of plasma progesterone by thin-layer and gas-liquid chromatography, Steroids, Volume: 12, Issue: 1, Pages: 63-86, 1968
Frequently Asked Questions
How can impurities be removed from Progesterone?
Progesterone impurities can be removed from Progesterone through various purification methods, including recrystallization, column chromatography, and solvent extraction.
What is the impact of Progesterone impurities on the stability of the drug?
Progesterone impurities can affect the stability of Progesterone, leading to its degradation and reduced efficacy.
What is the impact of Progesterone impurities on the drug’s shelf life?
Progesterone impurities can shorten the shelf life of Progesterone by accelerating the degradation of the compound.
How can Progesterone impurities affect the bioavailability of the drug?
Chemical interactions between Progesterone impurities and the active ingredient can alter the stability and solubility of Progesterone, leading to decreased bioavailability and efficacy of the drug. They can also react with other components of the drug formulation, leading to the formation of insoluble complexes that reduce absorption and distribution.
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