Nilotinib

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Nilotinib Impurity E CRS

  • CAT NUMBER DCTI-C-2957
  • CAS NUMBER 2119583-26-3
  • MOLECULAR FORMULA C27H20F3N7O
  • MOLECULAR WEIGHT 515.5

Nilotinib Impurity E. Formate

  • CAT NUMBER DCTI-C-3465
  • CAS NUMBER NA
  • MOLECULAR FORMULA C37H28F3N11O (Free Base); C38H30F3N11O3 (Formate salt)
  • MOLECULAR WEIGHT 699.7 (Free base); 745.73 (Formate salt)

Nilotinib Impurity F CRS

  • CAT NUMBER DCTI-C-2958
  • CAS NUMBER 2119583-24-1
  • MOLECULAR FORMULA C29H24F3N7O
  • MOLECULAR WEIGHT 543.55

Nilotinib impurity G CRS

  • CAT Number DCTI-C-1909
  • CAS Number 917392-54-2
  • Molecular Formula C18H16N4O2
  • Molecular Weight 320.35

Nilotinib N-Oxide

  • CAT Number DCTI-C-626
  • CAS Number 1246817-85-5
  • Molecular Formula C28H22F3N7O2
  • Molecular Weight 545.53

Nilotinib P36.5

  • CAT NUMBER DCTI-C-3637
  • CAS NUMBER 1807607-72-2
  • MOLECULAR FORMULA C28H20F3N7O3
  • MOLECULAR WEIGHT 559.51

Nilotinib P41.6

  • CAT NUMBER DCTI-C-3640
  • CAS NUMBER 1807606-80-9
  • MOLECULAR FORMULA C28H22F3N7O2
  • MOLECULAR WEIGHT 545.53

Nilotinib Regio isomer (Nilotinib impurity-9)

  • CAT Number DCTI-C-253
  • CAS Number 641571-15-5
  • Molecular Formula C28H22F3N7O
  • Molecular Weight 529.53

Nilotinib Related Impurity

  • CAT NUMBER DCTI-C-3466
  • CAS NUMBER NA
  • MOLECULAR FORMULA C26H20N8O2
  • MOLECULAR WEIGHT 476.5
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References
FAQ's

Frequently Asked Questions

Nilotinib impurities' control is through strict quality control measures during manufacturing. Regulatory authorities set specific limits for impurity levels that must be adhered to.

Nilotinib impurities can affect its effectiveness by altering the drug's pharmacokinetics, pharmacodynamics, or stability. It is crucial to control and monitor impurities so that the drug maintains its therapeutic potency and delivers the desired therapeutic outcomes.

Nilotinib generics are thoroughly checked for impurities to assure their quality, safety, and efficacy. Comparative studies and thorough quality control help guarantee that generic versions are equal regarding purity and drug efficacy.

Nilotinib impurities should be stored at a controlled room temperature between 2-8°C or as indicated on the Certificate of Analysis (CoA).

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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