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Minocycline
References
FAQ's
References
- Martell, Michael J. Jr.; Boothe, James H., 6-Deoxytetracyclines. VII. Alkylated aminotetracyclines possessing unique antibacterial activity, Journal of Medicinal Chemistry, Volume: 10, Issue: 1, Pages: 44-6, 1967
- De Leenheer, A. P.; Nelis, H. J. C. F., Liquid chromatographic determination of minocycline in human serum, Journal of Pharmaceutical Sciences, Volume: 68, Issue: 12, Pages: 1527-30, 1979,
Frequently Asked Questions
What methods help detect impurities in Minocycline?
High-performance liquid chromatography (HPLC), LC-MS, and UP-LC are commonly used analytical techniques for detecting and quantifying impurities in Minocycline.
What is the impact of impurities on the pharmacokinetics of Minocycline?
The Impurities in Minocycline can affect the pharmacokinetics through absorption, distribution, metabolism, and elimination.
Which solvent helps in the analysis of Minocycline impurities?
Methanol is a solvent that helps in analyzing most of the Minocycline impurities.
What are the temperature conditions required to store Minocycline impurities?
Minocycline impurities are stored at a controlled room temperature between 2-8 ⁰C or as indicated on the Certificate of Analysis (CoA).
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