Sort by

Lincomycin 2-Phosphate

  • CAS NUMBER 27480-30-4
  • MOLECULAR FORMULA C18H35N2O9PS (Free base); C20H39N2O11¬PS (Acetate salt)
  • MOLECULAR WEIGHT 486.52 (Free base); 546.20 (Acetate salt)

Lincomycin EP Impurity E Hydrochloride

  • CAS NUMBER 6734-79-8
  • MOLECULAR FORMULA C9H18ClNO2 (HCl salt); C9H17NO2 (free base)
  • MOLECULAR WEIGHT 207.7 (HCl salt); 171.24 (free base)

Lincomycin impurity A


Lincomycin Impurity C

  • CAS NUMBER 14600-41-0
  • MOLECULAR FORMULA C17H32N2O6S (free base); C17H33ClN2O6S (HCl salt)
  • MOLECULAR WEIGHT 392.51 (free base); 428.97 (HCl salt)

Lincomycin-2,4 -phosphate

  • CAT Number DCTI-C-675
  • CAS Number NA
  • Molecular Formula C18H33N2O8PS
  • Molecular Weight 468.5

General Information

Lincomycin Impurities and Lincomycin 

For evaluating the purity and safety of Lincomycin, an active pharmaceutical ingredient, Daicel Pharma offers a customized synthesis of Lincomycin impurity standards. These impurity standards include crucial compounds such as Lincomycin 2-Phosphate, Lincomycin EP Impurity E Hydrochloride, Lincomycin Impurity A, Lincomycin Impurity C, and Lincomycin-2,4 -phosphate. Additionally, Daicel Pharma provides worldwide delivery options for Lincomycin impurity standards.

Lincomycin [CAS: 154-21-2], derived from the bacteria Streptomyces Lincolnensis, is an antibiotic belonging to the lincosamide class. It exhibits efficacy against anaerobic bacteria and gram-positive bacteria. This antibiotic is from a variant of Streptomyces lincolnensis known as var. lincolnensis. It treats infections caused by staphylococci, streptococci, and Bacteroides fragilis bacteria.

Lincomycin: Use and Commercial Availability  

Lincocin is the brand name under which the drug, Lincomycin is available. It treats bacterial infections caused by susceptible streptococci, pneumococci, and staphylococci strains. The antibiotic is for patients allergic to penicillin or when penicillin is considered inappropriate. It is important to note that Lincomycin is for infections strongly suspected to be caused by bacteria susceptible to the drug, as with all antibacterial agents.

Lincomycin Structure and Mechanism of ActionLincomycin Structure and Mechanism of Action

The chemical name of Lincomycin is Methyl 6,8-dideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside. Its chemical formula is C18H34N2O6S, and its molecular weight is approximately 406.5 g/mol.

Lincomycin inhibits protein synthesis in susceptible organisms and prevents peptide bond formation.

Lincomycin Impurities and Synthesis

Impurities in Lincomycin refer to any substances in the Lincomycin drug product that are not in the desired active pharmaceutical ingredient (API). They may arise from various sources like manufacturing1, raw materials, or drug degradation over time. Common impurities found in Lincomycin include related compounds, residual solvents, and degradation products. The presence and levels of these impurities are carefully monitored and controlled during the manufacturing process to ensure the safety, efficacy, and quality of the Lincomycin drug product. Regulatory authorities have established guidelines and limits for impurity levels to ensure the purity of the drug and minimize potential adverse effects.

Daicel Pharma strictly adheres to cGMP standards and operates an analytical facility for preparing Lincomycin impurity standards, which include Lincomycin 2-Phosphate, Lincomycin EP Impurity E Hydrochloride, Lincomycin impurity A, Lincomycin Impurity C, and Lincomycin-2,4 -phosphate. Our Lincomycin impurity standards have a detailed Certificate of Analysis (CoA) that provides a comprehensive characterization report. This report includes data obtained through techniques,1H NMR, 13C NMR, IR, MASS, and HPLC purity analysis2. Upon request, we give additional data like 13C-DEPT. Moreover, we can synthesize unknown Lincomycin impurity standards and degradation products. Each delivery has a comprehensive characterization report.


Frequently Asked Questions

Strict quality control measures during manufacturing help monitor and control the levels of Lincomycin impurities. It includes rigorous testing, analysis, and adherence to regulatory guidelines.

Yes, impurities can contribute to the degradation of Lincomycin over time, potentially affecting its stability and shelf life. It is essential to minimize impurity levels to maintain the drug's quality and ensure its efficacy over its intended shelf life.

Water is a solvent used when analyzing many impurities in Lincomycin.

Lincomycin impurities should be stored, at a controlled room temperature, usually between 2-8 °C.

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

Back to Top
Product has been added to your cart