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Ibuprofen
References
FAQ's
References
- White, David R.; Wu, Daniel K., New synthesis of carboxylic acids from ketones, Journal of the Chemical Society, Chemical Communications, Issue: 23, Pages: 988-9, 1974
- Kaiser, David G.; Vangiessen, Garrett J., GLC [gas-liquid chromatography] determination of ibuprofen [(+-)-2-(p-isobutylphenyl)propionic acid] in plasma, Journal of Pharmaceutical Sciences, Volume: 63, Issue: 2, Pages: 219-21, 1974
Frequently Asked Questions
Can Ibuprofen impurities cause adverse effects or reduce its effectiveness?
If the presence of impurities in Ibuprofen is within acceptable limits, there is no cause for adverse effects or its impact on effectiveness. However, higher impurity levels could affect the drug's safety and efficacy.
Can the presence of impurities vary between different brands of Ibuprofen?
While different brands of Ibuprofen may vary in manufacturing processes and quality control measures, all formulations must comply with regulatory standards for impurity levels. Therefore, the presence of impurities should be within acceptable limits regardless of the brand.
Which solvent helps in analyzing Ibuprofen impurities?
Acetonitrile or Methanol are the commonly used solvents when analyzing many impurities in Ibuprofen.
How should Ibuprofen impurities be stored in terms of temperature?
The recommendation is to store Ibuprofen impurities at a controlled room temperature, within 2-8 °C.
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