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Cabozantinib
References
FAQ's
References
- Bannen, Lynne Canne; Chan, Diva Sze-ming; Chen, Jeff; Dalrymple, Lisa Esther; Forsyth, Timothy Patrick; Huynh, Tai Phat; Jammalamadaka, Vasu; Khoury, Richard George; Leahy, James William; Mac, Morrison B.; et al, C-MET Modulators And Methods Of Use, Exelixis, Inc., United States, WO2005030140A2, April 7. 2005 (https://patents.google.com/patent/WO2005030140A2/en)
- Wu, Chunyong; Xu, Xue; Feng, Chao; Shi, Yuanyuan; Liu, Wenyuan; Zhu, Xiaoyun; Zhang, Junying, Degradation kinetics study of cabozantinib by a novel stability-indicating LC method and identification of its major degradation products by LC/TOF-MS and LC-MS/MS, Journal of Pharmaceutical and Biomedical Analysis, Volume: 98, Pages: 356-363, 2014
Frequently Asked Questions
Why are impurities in Cabozantinib a concern?
Cabozantinib impurities can have unknown pharmacological effects and can potentially harm patients, so it's essential to identify and control them.
Can Cabozantinib impurities be removed from the drug product?
Cabozantinib impurities cannot be removed from the drug product, but their levels can be minimized through effective manufacturing processes and monitoring.
How often are impurities in Cabozantinib monitored?
Cabozantinib impurities are monitored throughout the manufacturing process and over the shelf life of the drug product to ensure that their levels remain within acceptable limits.
What are the temperature conditions required to store Cabozantinib impurities?
Cabozantinib impurities are stored at a controlled room temperature between 2-8 °C or as indicated on the Certificate of Analysis (CoA).
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