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Mirabegron - NDSRI's
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N-Nitroso Mirabegron

  • CAT NUMBER DCTI-C-2363
  • CAS NUMBER NA
  • MOLECULAR FORMULA C21H23N5O3S
  • MOLECULAR WEIGHT 425.5
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N-Nitroso Mirabegron S-Isomer

  • CAT NUMBER DCTI-C-2556
  • CAS NUMBER NA
  • MOLECULAR FORMULA C21H23N5O3S (free base)
  • MOLECULAR WEIGHT 425.5 (Free base)
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(R)-N-(2-hydroxy-2-phenylethyl)-N-(4-nitrophenethyl)nitrous amide

  • CAT Number DCTI-C-4475
  • CAS Number 3032026-53-9
  • Molecular Formula C17H17N2O4
  • Molecular Weight 313.33
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(R)-N-(4-aminophenethyl)-N-(2-hydroxy-2-phenylethyl)nitrous amide

  • CAT Number DCTI-C-4482
  • CAS Number 3032026-54-0
  • Molecular Formula C16H19N3O2
  • Molecular Weight 285.35
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References
FAQ's

References

  1. Maruyama, Tatsuya; Suzuki, Takayuki; Onda, Kenichi; Hayakawa, Masahiko; Moritomo, Hiroyuki; Kimizuka, Tetsuya; Matsui, Tetsuo, Amide Derivatives Or Salts Thereof, Yamanouchi Pharmaceutical Co., Ltd., Japan, EP1028111B1, May 12, 2004
  2. van Teijlingen, Raymond; Meijer, John; Takusagawa, Shin; van Gelderen, Marcel; van den Beld, Cas; Usui, Takashi, Development and validation of LC-MS/MS methods for the determination of mirabegron and its metabolites in human plasma and their application to a clinical pharmacokinetic study, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, Volume: 887-888, Pages: 102-111,2012

Frequently Asked Questions

Mirabegron impurities removal from the drug product involves various manufacturing processes such as recrystallization, filtration, or chromatography. However, the impurity removal process needs to be validated and effective without affecting the safety and efficacy of the drug product.

High levels of Mirabegron impurities can harm patients. Therefore, it is necessary to control the impurity levels to ensure drug safety.

Methanol is a solvent used for analyzing many impurities in Mirabegron.

Mirabegron impurities are stored at a controlled room temperature between 2-8 ⁰C or as indicated on the Certificate of Analysis (CoA).

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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