Doxycycline - NDSRI's

N-nitroso-desmethyldoxycycline Acetate

  • MOLECULAR FORMULA C21H21N3O9 (Free base); C23H25N3O11 (Acetate salt)
  • MOLECULAR WEIGHT 459.41(Free base); 519.46 (Acetate salt)

Frequently Asked Questions

The LC method involves the separation of impurities present in Doxycycline by passing a mixture of the sample and a mobile phase through a chromatographic column. The separated impurities are detected and quantified using a detector. The LC method helps in identifying and quantifying organic and inorganic impurities. This method is selective, precise, and accurate for determining impurities in Doxycycline.

The most common impurities in Doxycycline are related substances formed during manufacturing, such as 4-Epidoxycycline and 6-Epidoxycycline.

Methanol is a solvent for analyzing Doxycycline impurities.

Doxycycline impurities should be stored at a controlled room temperature between 2-8 ⁰C or as indicated on the Certificate of Analysis (CoA).

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