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Carbidopa - NDSRI's
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N-Nitroso Carbidopa Acetate Salt

  • CAT NUMBER DCTI-C-3658
  • CAS NUMBER NA
  • MOLECULAR FORMULA Free Acid: C10H13N3O5 Acetate Salt: Chemical Formula: C12H17N3O7-
  • MOLECULAR WEIGHT Free Acid: 255.23 Acetate Salt: 315.28
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References
FAQ's

References

  1. Bayne, Gilbert M., Composition and Method Of Treating Dopamine Deficiency In Brain Tissue, Merck and Co., Inc., US3769424A, October 30, 1973
  2. Karady, Sandor; Ly, Manuel G.; Pines, Seemon H.; Sletzinger, Meyer, Synthesis of D- and L-α-(3,4-dihydroxybenzyl)-α-hydrazinopropionic acid via resolution, Journal of Organic Chemistry, Volume: 36, Issue: 14, Pages: 1946-8, 1971
  3. Vickers, S.; Stuart, E. K., Spectrofluorometric determination of carbidopa [L-(-)-α-hydrazino-3,4-dihydroxy-α-methylhydrocinnamic acid] in plasma, Journal of Pharmaceutical Sciences, Volume: 62, Issue: 9, Pages: 1550-1, 1973

Frequently Asked Questions

The methods used to detect and quantify impurities in Carbidopa include high-performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS). These methods can identify and measure impurities at low levels, typically in the parts per million (ppm) range.

The source of impurities in Carbidopa includes starting materials, reagents, catalysts, solvents, etc. The contamination also occurs during storage and transportation.

The impurities in Carbidopa vary between batches of the drug, depending on factors such as the manufacturing process, the quality of the starting materials, storage, and transportation. Therefore, it is essential to test each batch of Carbidopa for impurities and ensure that it meets the regulatory requirements before its use.

Carbidopa impurities are stored at a controlled room temperature between 2-8 ⁰C or as indicated on the Certificate of Analysis (CoA).

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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