Hydrochlorothiazide - NDSRI's
References
FAQ's
References
- Process for the manufacture of benzothiadiazines, GB880652A, Jul 31, 1958, CIBA Ltd (https://www.lens.org/lens/search/patent/list?q=GB880652A)
- VandenHeuvel, W. J. A.; Gruber, V. F.; Walker, R. W.; Wolf, F. J., GLC [gas-liquid chromatographic] analysis of hydrochlorothiazide in blood and plasma, Journal of Pharmaceutical Sciences, Volume: 64, Issue: 8, Pages: 1309-12, 1975 DOI: (10.1002/jps.2600640810)
Frequently Asked Questions
2.What is the potential Hydrochlorothiazide impurity that forms in the drug substance?
Hydrochlorothiazide-CH2- Hydrochlorothiazide isomer is the potential Hydrochlorothiazide impurity that forms in the drug substance.
3.Which analytical methods identify and analyze Hydrochlorothiazide impurities?
Ultraviolet spectroscopy, liquid chromatography/mass spectrometry, and 1H and 13C nuclear magnetic resonance (NMR) spectroscopy identify Hydrochlorothiazide impurities. RP-HPLC helps analyze Hydrochlorothiazide impurities.
4.Under which conditions do the Hydrochlorothiazide degradation products form?
Hydrochlorothiazide degradation products form under photolytic conditions.
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