Prednisolone

Sort by

1,2-Dihydro Loteprednol

  • CAT Number DCTI-C-139
  • CAS Number 82034-20-6
  • Molecular Formula C24H33ClO7
  • Molecular Weight 468.97

11-ß-hydroxy-1,4-dien-3,17-androstendione

  • CAT Number DCTI-C-1504
  • CAS Number 898-84-0
  • Molecular Formula C19H24O3
  • Molecular Weight 300.4

17 Acid 17 ethyl carbonate prednisolone

  • CAT Number DCTI-C-134
  • CAS Number 133991-63-6
  • Molecular Formula C23H30O7
  • Molecular Weight 418.49

6,7-Dehydro prednisolone 24-Acetate

  • CAT NUMBER DCTI-C-2607
  • CAS NUMBER 2427-45-4
  • MOLECULAR FORMULA C23H28O6
  • MOLECULAR WEIGHT 400.47

Diacetyl Prednisolone

  • CAT Number DCTI-C-715
  • CAS Number 98523-85-4
  • Molecular Formula C25H32O7
  • Molecular Weight 444.52

Difluoroprednisolone-3(10H) one

  • CAT NUMBER DCTI-C-2682
  • CAS NUMBER NA
  • MOLECULAR FORMULA C19H22F2O3
  • MOLECULAR WEIGHT 336.38

Hydrocortisone / Pregn-4-ene-3,20-dione,11,17,21-trihydroxy-,(11β)

  • CAT Number DCTI-C-841
  • CAS Number 50-23-7
  • Molecular Formula C21H30O5
  • Molecular Weight 362.47

Loteprednol 1,2 Dihydro ethyl carbonate

  • CAT Number DCTI-C-140
  • CAS Number 82048-81-5
  • Molecular Formula C26H36O9
  • Molecular Weight 492.57

Loteprednol Dimer

  • CAT Number DCTI-C-1505
  • CAS Number NA
  • Molecular Formula C47H60O14
  • Molecular Weight 848.98
LOAD MORE
You're viewed 9 of 23 products

General Information

Prednisolone Impurities and Prednisolone

Daicel Pharma specializes in providing Prednisolone impurity standards such as 1,2-Dihydro Loteprednol, Difluoroprednisolone-3(10H) one, Prednisolone 1,2-Propane diol protected Impurity, Prednisolone 17B hydroxy acid, Prednisolone di carbonate 1NH, Prednisolone-21-ethylcarbonate, Prednisolone 20 ethyl ester 1NH, Prednisolone Ph. Eur. Impurity E, Prednisolone Z-enol aldehyde Impurity, and more. Their presence can impact the efficacy, quality, and safety of Prednisolone. Daicel Pharma custom prepares Prednisolone impurities and delivers them globally.

Prednisolone [CAS: 50-24-8] is a glucocorticoid derived from prednisone. It functions as an adrenergic agent, anti-inflammatory medication, antineoplastic treatment, and drug metabolite. Prednisolone treats many conditions, such as allergic disorders, skin conditions, autoimmune diseases, respiratory diseases, and types of cancers.

Prednisolone: Use and Commercial Availability

Prednisolone treats various medical conditions, including endocrine, rheumatic, and hematologic disorders, collagen and dermatologic diseases, ophthalmic and respiratory ailments, gastrointestinal disorders, allergic reactions, edematous states, and additional conditions such as tuberculous meningitis. This drug is available under various tradenames like Cortalone, Fernisolone-P, Hydeltra-TBA, Meti-Derm, Meticortelone, Omnipred, Pred Forte, Pred Mild, Prelone, Sterane, and many more.

Prednisolone Structure and Mechanism of ActionPrednisolone Structure and Mechanism of Action 

The chemical name of Prednisolone is (11β)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione. Its chemical formula is C21H28O5, and its molecular weight is approximately 360.4 g/mol.

The mechanism of action of Prednisolone is poorly understood.

Prednisolone Impurities and Synthesis

Prednisolone impurities are unwanted substances in drug formulations, either as byproducts of the synthetic process1 or as impurities introduced during manufacturing or storage. These impurities can affect the quality, safety, and efficacy of Prednisolone.

Daicel Pharma provides a Certificate of Analysis (CoA) for Prednisolone impurity standards such as 1,2-Dihydro Loteprednol, Difluoroprednisolone-3(10H) one, Prednisolone 1,2-Propane diol protected Impurity, Prednisolone 17B hydroxy acid, Prednisolone di carbonate 1NH, Prednisolone-21-ethylcarbonate, Prednisolone 20 ethyl ester 1NH, Prednisolone Ph. Eur. Impurity E, Prednisolone Z-enol aldehyde Impurity, and more. Daicel Pharma offers a cGMP-certified analytical laboratory that provides the CoA, which includes thorough characterization data including 1H NMR, 13C NMR, IR, MASS, and HPLC purity2. On request, we give more characterization details, such as those for 13C-DEPT. At Daicel Pharma, we synthesize Prednisolone impurities.

References
FAQ's

Frequently Asked Questions

Prednisolone impurities can affect its pharmacological activity by altering the drug's potency, efficacy, bioavailability, and potential for adverse effects.

Yes, impurities in Prednisolone can potentially impact its stability or shelf life.

Impurities in Prednisolone can compromise its quality and safety by potentially altering its pharmacological activity, causing adverse effects, and reducing therapeutic efficacy.

Prednisolone impurities are stored preferably at a regulated room temperature of 2-8°C or as specified on the Certificate of Analysis (CoA).

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

Back to Top
Product has been added to your cart